| چکیده انگلیسی مقاله |
The purpose of present study was to survey effect of a period of strength training on serum chemerin concentration and insulin resistance in inactive young obese men. Materials & Methods: In a semi-experimental study, twenty one inactive young obese men were randomly placed at two groups: strength training (n=10, 26.7 ± 3.3 yr, 96.1 ± 5.5 kg, 31.2 ± 2.9 %, 32.6 ± 2.8 kg/m2) and control (n=11, 28.1 ± 3.7 yr, 95.7 ± 5.7 kg, 30.9 ± 3.2 %, 32.1 ± 3.7 kg/m2). Weight, fat percent, body mass index, circulating levels of chemerin, insulin, and glucose, and insulin resistance index (HOMA-IR) were assessed before and after the training. Strength training protocol consisted of twelve weeks weight training. Data were analyzed by SPSS16 software and using Independent and Paired t-tests and Pearson's correlation analysis. Results: Strength training significantly decreased serum concentrations of chemerin (P=0.011), insulin (P=0.013) and HOMA-IR (P=0.007), while serum glucose concentration didn’t change significantly. Also, changes of serum chemerin concentration following the training was directly correlated to changes of serum insulin concentration (r=0.51, p=0.012) and HOMA-IR (r=0.52, p=0.027), while didn’t show significant correlation with serum glucose concentration. Conclusion: It appears that, via decrease of circulating levels of chemerin and insulin and insulin resistance, strength training can reduce the risk of cardiovascular and metabolic diseases in inactive young obese men. According to findings of the study, changes of serum chemerin levels following strength training has direct correlations with changes of serum levels of insulin and insulin resistance. |